Prostaglandin FP receptor inhibitor reduces ischemic brain damage and neurotoxicity

Bioactive lipids such as the prostaglandins have been reported to have various cytoprotective or toxic properties in acute and chronic neurological conditions. The roles of PGF2α and its receptor (FP) are not clear in the pathogenesis of ischemic brain injury. Considering that this G-protein coupled...

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Bibliographic Details
Main Authors: Yun Tai Kim, Sang Kwan Moon, Takayuki Maruyama, Shuh Narumiya, Sylvain Doré
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002112