A repetitive DNA element regulates expression of the Helicobacter pylori sialic acid binding adhesin by a rheostat-like mechanism.

During persistent infection, optimal expression of bacterial factors is required to match the ever-changing host environment. The gastric pathogen Helicobacter pylori has a large set of simple sequence repeats (SSR), which constitute contingency loci. Through a slipped strand mispairing mechanism, t...

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Bibliographic Details
Main Authors: Anna Åberg, Pär Gideonsson, Anna Vallström, Annelie Olofsson, Carina Öhman, Lena Rakhimova, Thomas Borén, Lars Engstrand, Kristoffer Brännström, Anna Arnqvist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4081817?pdf=render