Urinary Extracellular Domain of Neurotrophin Receptor p75 as a Biomarker for Amyotrophic Lateral Sclerosis in a Chinese cohort

Abstract To comprehensively assess whether p75ECD in urine could be a candidate biomarker for ALS evaluation. Urine samples were collected from 101 ALS patients, 108 patients with other neurological disease (OND) and 97 healthy controls. 61 ALS patients were followed up with clinical data including...

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Bibliographic Details
Main Authors: Rui Jia, Stephanie Shepheard, Jiaoting Jin, Fangfang Hu, Xing Zhao, Li Xue, Li Xiang, Huaguang Qi, Qiumin Qu, Feng Guo, Mary-Louise Rogers, Jingxia Dang
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05430-w