Do opioid receptors play a role in the pathogenesis of the inflammatory response in acute pancreatitis? Os receptores opioides desempenham papel na patogênese da resposta inflamatória na pancreatite aguda?

Do opioid receptors play a role in the pathogenesis of the inflammatory response in acute pancreatitis? Os receptores opioides desempenham papel na patogênese da resposta inflamatória na pancreatite aguda?

PURPOSE: To investigate the effect of the opioid blocker naltrexone in the inflammatory response in acute pancreatitis (AP). METHODS: Acute pancreatitis was induced in anesthetized male Wistar rats by retrograde injection of 2.5% sodium taurocholate diluted in 0.5ml saline into the main pancreatic d...

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Bibliographic Details
Main Authors: Artur Penido, Ana Maria Mendonça Coelho, Nilza Trindade Molan, Fabiano Pinheiro da Silva, Luiz Augusto Carneiro D'Albuquerque, Marcel Cerqueira Cesar Machado
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2012-09-01
Series:Acta Cirurgica Brasileira
Subjects:
Pancreatite
Fisiopatologia
Receptores Opióides
Naltrexona
Ratos
Pancreatitis
Physiopathology
Receptors, Opioid
Naltrexone
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000900002

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000900002

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