Cell Membrane and Electron Transfer Engineering for Improved Synthesis of Menaquinone-7 in Bacillus subtilis

Summary: The formation of biofilm facilitates the synthesis of valuable natural product menaquinone-7 (MK-7) in static culture of Bacillus subtilis, whereas the essential role and mechanism of biofilm in MK-7 synthesis have not been revealed. Herein, comparative transcriptomics show that the formati...

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Bibliographic Details
Main Authors: Shixiu Cui, Hongzhi Xia, Taichi Chen, Yang Gu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Long Liu
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220301024