Increasing sequence search sensitivity with transitive alignments.

Sequence alignment is an important bioinformatics tool for identifying homology, but searching against the full set of available sequences is likely to result in many hits to poorly annotated sequences providing very little information. Consequently, we often want alignments against a specific subse...

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Bibliographic Details
Main Authors: Ketil Malde, Tomasz Furmanek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3573025?pdf=render