Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight

Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight

Increasing evidence indicates the occurrence of cognitive impairment in astronauts under spaceflight compound conditions, but the underlying mechanisms and countermeasures need to be explored. In this study, we found that learning and memory abilities were significantly reduced in rats under a simul...

Full description

Bibliographic Details
Main Authors: Xiaorui Wu, Dong Li, Junlian Liu, Lihong Diao, Shukuan Ling, Yuheng Li, Jianyi Gao, Quanchun Fan, Weijia Sun, Qi Li, Dingsheng Zhao, Guohui Zhong, Dengchao Cao, Min Liu, Jiaping Wang, Shuang Zhao, Yu Liu, Guie Bai, Hongzhi Shi, Zi Xu, Jing Wang, Chunmei Xue, Xiaoyan Jin, Xinxin Yuan, Hongxing Li, Caizhi Liu, Huiyuan Sun, Jianwei Li, Yongzhi Li, Yingxian Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Pharmacology
Subjects:
dammarane sapogenins
cognitive
space flight
rat models
neurotransmitter
MAPK
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00315/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00315/full

Similar Items