Using in vivo oxidation status of one- and two-component redox relays to determine H2O2 levels linked to signaling and toxicity

Abstract Background Hydrogen peroxide (H2O2) is generated as a by-product of metabolic reactions during oxygen use by aerobic organisms, and can be toxic or participate in signaling processes. Cells, therefore, need to be able to sense and respond to H2O2 in an appropriate manner. This is often acco...

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Bibliographic Details
Main Authors: Alba Domènech, José Ayté, Fernando Antunes, Elena Hidalgo
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-018-0523-6