Dapagliflozin effect on endothelial dysfunction in diabetic patients with atherosclerotic disease: a randomized active-controlled trial

Dapagliflozin effect on endothelial dysfunction in diabetic patients with atherosclerotic disease: a randomized active-controlled trial

Abstract Background The glucose-lowering independent effect of sodium glucose cotransporter-2 inhibitors (SGLT2i) on arterial wall function has not yet been clarified. This study aims to assess whether SGLT2i treatment can attenuate endothelial dysfunction related to type 2 diabetes mellitus (T2D) c...

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Bibliographic Details
Main Authors: Andrei C. Sposito, Ikaro Breder, Alexandre A. S. Soares, Sheila T. Kimura-Medorima, Daniel B. Munhoz, Riobaldo M. R. Cintra, Isabella Bonilha, Daniela C. Oliveira, Jessica Cunha Breder, Pamela Cavalcante, Camila Moreira, Filipe A. Moura, Jose Carlos de Lima-Junior, Helison R. P. do Carmo, Joaquim Barreto, Wilson Nadruz, Luiz Sergio F. Carvalho, Thiago Quinaglia, ADDENDA-BHS2 trial investigators
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Cardiovascular Diabetology
Subjects:
SGLT2
Endothelial function
Type 2 diabetes
Nitric oxide
Online Access:https://doi.org/10.1186/s12933-021-01264-z

Internet

https://doi.org/10.1186/s12933-021-01264-z

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