Bias detection and correction in RNA-Sequencing data

<p>Abstract</p> <p>Background</p> <p>High throughput sequencing technology provides us unprecedented opportunities to study transcriptome dynamics. Compared to microarray-based gene expression profiling, RNA-Seq has many advantages, such as high resolution, low backgrou...

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Bibliographic Details
Main Authors: Zhao Hongyu, Chung Lisa M, Zheng Wei
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/290