Hspa13 Promotes Plasma Cell Production and Antibody Secretion

Hspa13 Promotes Plasma Cell Production and Antibody Secretion

The generation of large numbers of plasma cells (PCs) is a main factor in systemic lupus erythematosus (SLE). We hypothesize that Hspa13, a member of the heat shock protein family, plays a critical role in the control of PC differentiation. To test the hypothesis, we used lipopolysaccharide (LPS)-ac...

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Bibliographic Details
Main Authors: Youdi He, Ruonan Xu, Bing Zhai, Ying Fang, Chunmei Hou, Chen Xing, He Xiao, Guojiang Chen, Xiaoqian Wang, Ning Ma, Gencheng Han, Renxi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
Hspa13
SLE
B cells
plasma cells
antibody
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00913/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00913/full

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