Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer.

Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer.

Clinical application of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based cancer therapeutics has not reached optimal potencies in part due to inadequate drug stability and inefficiencies in cancer-selective drug delivery. As such, innovative strategies regarding drug design and...

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Bibliographic Details
Main Authors: Lindsay M Kuroki, Xingjian Jin, Igor P Dmitriev, Elena A Kashentseva, Matthew A Powell, David G Mutch, Allan B Dietz, David T Curiel, William G Hawkins, Dirk Spitzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5739501?pdf=render

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http://europepmc.org/articles/PMC5739501?pdf=render

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