C-reactive protein does not opsonize early apoptotic human neutrophils, but binds only membrane-permeable late apoptotic cells and has no effect on their phagocytosis by macrophages

<p>Abstract</p> <p>Background</p> <p>It has been reported that C-reactive protein (CRP) binds both leukocyte FcγRIIA (CD32) and the plasma membrane of apoptotic cells. Since FcγRIIA becomes functionally enabled during neutrophil apoptosis, we sought to determine whether...

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Bibliographic Details
Main Authors: MacCall Shonna M, Alexander Karen M, Hart Simon P, Dransfield Ian
Format: Article
Language:English
Published: BMC 2005-05-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/2/1/5