The effects Metformin/Irinotecan-loaded PLGA nanoparticles on glutamate re-uptake time and alteration EAAT1 gene expression level in vitro

The effects Metformin/Irinotecan-loaded PLGA nanoparticles on glutamate re-uptake time and alteration EAAT1 gene expression level in vitro

Objective(s): The present study was designed to evaluate of Metformin/Irinotecan-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles (NPs) effects on glutamate re-uptake time and receptor expression status in both glioblastoma multiforme (GBM) and cortex neuron cultures. The study was performed...

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Bibliographic Details
Main Authors: Ali Taghizadehghalehjoughi, Ahmet Hacimuftuoglu, Meltem Cetin, Afifie ugur, Selcuk butuner, Numan Taspinar, Maryam mohammadzadeh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2019-01-01
Series:Nanomedicine Journal
Subjects:
EAAT1
Irinotecan
Metformin
PLGA
Voltammetry
Online Access:http://nmj.mums.ac.ir/article_12156_3f3a522aa6990031fc177ebaed125a1c.pdf

Internet

http://nmj.mums.ac.ir/article_12156_3f3a522aa6990031fc177ebaed125a1c.pdf

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