Axin downregulates TCF-4 transcription via β-catenin, but not p53, and inhibits the proliferation and invasion of lung cancer cells

<p>Abstract</p> <p>Background</p> <p>We previously reported that overexpression of Axin downregulates T cell factor-4 (TCF-4) transcription. However, the mechanism(s) by which Axin downregulates the transcription and expression of TCF-4 is not clear. It has been reporte...

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Bibliographic Details
Main Authors: Miao Yuan, Dong Qian-Ze, Yang Zhi-Qiang, Zhao Yue, Liu Yang, Li Qing-Chang, Han Yang, Xu Hong-Tao, Yang Lian-He, Dai Shun-Dong, Wang En-Hua
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/25