A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?

The phosphoinositide 3-kinase and AKT (Protein Kinase B, PKB) signalling pathway (PI3K/AKT) plays a central role in the control of cell survival, growth and proliferation throughout the body. With regard to bone, and in particularly in osteoblasts, there is an increasing amount of evidence that the...

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Bibliographic Details
Main Authors: Imelda Mary McGonnell, Agamemnon Emil Grigoriadis, Eric W-F. Lam, Joanne S Price, Andrew eSunters
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Endocrinology
Subjects:
Akt
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00088/full