Phosphatidylinositol-3,4,5-Triphosphate and Cellular Signaling: Implications for Obesity and Diabetes

Phosphatidylinositol-3,4,5-Triphosphate and Cellular Signaling: Implications for Obesity and Diabetes

Phosphatidylinositol-3,4,5-triphosphate (PtdIns(3,4,5)P3) is one of the most important phosphoinositides and is capable of activating a wide range of proteins through its interaction with their specific binding domains. Localization and activation of these effector proteins regulate a number of cell...

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Bibliographic Details
Main Authors: Prasenjit Manna, Sushil K. Jain
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
PtdIns(3,4,5)P3
PI3K/PTEN equilibria
PH domain-containing proteins
Insulin resistance
Cardiovascular complications
Vascular inflammation
Online Access:http://www.karger.com/Article/FullText/373949

Internet

http://www.karger.com/Article/FullText/373949

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