Inhibition of sarcoplasmic Ca<sup>2+</sup>-ATPase increases caffeine- and halothane-induced contractures in muscle bundles of malignant hyperthermia susceptible and healthy individuals
<p>Abstract</p> <p>Background</p> <p>Malignant hyperthermia (MH) is triggered by halogenated anaesthetics and depolarising muscle relaxants, leading to an uncontrolled hypermetabolic state of skeletal muscle. An uncontrolled sarcoplasmic Ca<sup>2+ </sup>rele...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-06-01
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| Series: | BMC Anesthesiology |
| Online Access: | http://www.biomedcentral.com/1471-2253/5/8 |