Regulated protein aggregation: stress granules and neurodegeneration

<p>Abstract</p> <p>The protein aggregation that occurs in neurodegenerative diseases is classically thought to occur as an undesirable, nonfunctional byproduct of protein misfolding. This model contrasts with the biology of RNA binding proteins, many of which are linked to neurodeg...

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Bibliographic Details
Main Author: Wolozin Benjamin
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Molecular Neurodegeneration
Subjects:
TTP
FUS
Online Access:http://www.molecularneurodegeneration.com/content/7/1/56