Bulleyaconitine A Inhibits Visceral Nociception and Spinal Synaptic Plasticity through Stimulation of Microglial Release of Dynorphin A

Background. Visceral pain is one of the most common types of pain and particularly in the abdomen is associated with gastrointestinal diseases. Bulleyaconitine A (BAA), isolated from Aconitum bulleyanum, is prescribed in China to treat chronic pain. The present study is aimed at evaluating the mecha...

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Bibliographic Details
Main Authors: Sheng-Nan Huang, Jinbao Wei, Lan-Ting Huang, Pei-Jun Ju, Jinghong Chen, Yong-Xiang Wang
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2020/1484087