Derivation and Characterization of Immortalized Human Muscle Satellite Cell Clones from Muscular Dystrophy Patients and Healthy Individuals

Derivation and Characterization of Immortalized Human Muscle Satellite Cell Clones from Muscular Dystrophy Patients and Healthy Individuals

In Duchenne muscular dystrophy (DMD) patients, absence of dystrophin causes muscle wasting by impacting both the myofiber integrity and the properties of muscle stem cells (MuSCs). Investigation of DMD encompasses the use of MuSCs issued from human skeletal muscle. However, DMD-derived MuSC usage is...

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Bibliographic Details
Main Authors: Jimmy Massenet, Cyril Gitiaux, Mélanie Magnan, Sylvain Cuvellier, Arnaud Hubas, Patrick Nusbaum, F Jeffrey Dilworth, Isabelle Desguerre, Bénédicte Chazaud
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
human muscle stem cells
immortalization
degenerative myopathies
Duchenne muscular dystrophy
congenital myopathies
Online Access:https://www.mdpi.com/2073-4409/9/8/1780

Internet

https://www.mdpi.com/2073-4409/9/8/1780

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