A phytol-enriched diet induces changes in fatty acid metabolism in mice both via PPARα-dependent and -independent pathways

A phytol-enriched diet induces changes in fatty acid metabolism in mice both via PPARα-dependent and -independent pathways

Branched-chain fatty acids (such as phytanic and pristanic acid) are ligands for the nuclear hormone receptor peroxisome proliferator-activated receptor α (PPARα) in vitro. To investigate the effects of these physiological compounds in vivo, wild-type and PPARα-deficient (PPARα−/−) mice were fed a p...

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Bibliographic Details
Main Authors: J. Gloerich, N. van Vlies, G.A. Jansen, S. Denis, J.P.N. Ruiter, M.A. van Werkhoven, M. Duran, F.M. Vaz, R.J.A. Wanders, S. Ferdinandusse
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Journal of Lipid Research
Subjects:
peroxisome proliferator-activated receptor α
peroxisomes
mitochondria
fatty acid β-oxidation
very long-chain fatty acids
branched-chain fatty acids
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340062

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http://www.sciencedirect.com/science/article/pii/S0022227520340062

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