Pathophysiological Effects of Synthetic Derivatives of Polymeric Alkylpyridinium Salts from the Marine Sponge, Reniera sarai

Pathophysiological Effects of Synthetic Derivatives of Polymeric Alkylpyridinium Salts from the Marine Sponge, Reniera sarai

Polymeric 3-alkylpyridinium salts (poly-APS) are among the most studied natural bioactive compounds extracted from the marine sponge, Reniera sarai. They exhibit a wide range of biological activities, and the most prominent among them are the anti-acetylcholinesterase and membrane-damaging activity...

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Bibliographic Details
Main Authors: Marjana Grandič, Robert Frangež
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Marine Drugs
Subjects:
alkylpyridinium compounds
APS12-2
APS3
cardiotoxicity
hemolysis
nicotinic acetylcholine receptors
neuromuscular junction
mouse
rat
synthesis
Online Access:http://www.mdpi.com/1660-3397/12/5/2408

Internet

http://www.mdpi.com/1660-3397/12/5/2408

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