Predicting antigen specificity of single T cells based on TCR CDR3 regions
Abstract It has recently become possible to simultaneously assay T‐cell specificity with respect to large sets of antigens and the T‐cell receptor sequence in high‐throughput single‐cell experiments. Leveraging this new type of data, we propose and benchmark a collection of deep learning architectur...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-08-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.20199416 |