SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy
Abstract Denervation of skeletal muscles results in a rapid and programmed loss of muscle size and performance, termed muscle atrophy, which leads to a poor prognosis of clinical nerve repair. Previous researches considered this process a result of multiple factors, such as protein homeostasis disor...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-04094-9 |