Recombinant Salmonella expressing SspH2-EscI fusion protein limits its colonization in mice

Recombinant Salmonella expressing SspH2-EscI fusion protein limits its colonization in mice

Abstract Background Activation of inflammasome contributes to the clearance of intracellular bacteria. C-terminus of E. coli EscI protein can activate NLRC4 (NLR family, CARD domain containing-4) inflammasome in macrophages. The purpose of this study was to determine if activation of NLRC4 inflammas...

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Bibliographic Details
Main Authors: Maozhi Hu, Weixin Zhao, Wei Gao, Wenhua Li, Chuang Meng, Qiuxiang Yan, Yuyang Wang, Xiaohui Zhou, Shizhong Geng, Zhiming Pan, Guiyou Cui, Xinan Jiao
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Immunology
Subjects:
Salmonella
Inflammasome
SspH2-EscI
Mice
Colonization
Online Access:http://link.springer.com/article/10.1186/s12865-017-0203-2

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http://link.springer.com/article/10.1186/s12865-017-0203-2

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