Different Roles of GRP78 on Cell Proliferation and Apoptosis in Cartilage Development

Different Roles of GRP78 on Cell Proliferation and Apoptosis in Cartilage Development

Eukaryotic cells possess several mechanisms to adapt to endoplasmic reticulum (ER) stress and thereby survive. ER stress activates a set of signaling pathways collectively termed as the unfolded protein response (UPR). We previously reported that Bone morphogenetic protein 2 (BMP2) mediates mild ER...

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Bibliographic Details
Main Authors: Zhangyuan Xiong, Rong Jiang, Xiangzhu Li, Yanna Liu, Fengjin Guo
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:International Journal of Molecular Sciences
Subjects:
GRP78
ER stress
apoptosis
unfolded protein response
cartilage development
Online Access:http://www.mdpi.com/1422-0067/16/9/21153

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http://www.mdpi.com/1422-0067/16/9/21153

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