A review of application of base editing for the treatment of inner ear disorders

Abstract. The development of applications for the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease 9) system has increased greatly in recent years, especially in the area of gene therapy by efficient in vivo genome editing. Although great success has...

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Bibliographic Details
Main Authors: Xingle Zhao, Zhuoer Sun, Wen Kang, Yong Tao, Hao Wu
Format: Article
Language:English
Published: Wolters Kluwer Health 2020-06-01
Series:Journal of Bio-X Research
Online Access:http://journals.lww.com/10.1097/JBR.0000000000000040