Pharmacological activation of TAZ enhances osteogenic differentiation and bone formation of adipose-derived stem cells

Pharmacological activation of TAZ enhances osteogenic differentiation and bone formation of adipose-derived stem cells

Abstract Background Adipose-derived stem cells (ADSCs) are an attractive cell source for bone tissue engineering and have great potential for bone regeneration and defect repair. The transcriptional coactivator with PDZ-binding motif (TAZ) has been demonstrated to modulate osteogenic and adipogenic...

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Bibliographic Details
Main Authors: Yumin Zhu, Yaping Wu, Jie Cheng, Qiong Wang, Zhongwu Li, Yanling Wang, Dongmiao Wang, Hua Wang, Weibing Zhang, Jinhai Ye, Hongbing Jiang, Lin Wang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Stem Cell Research & Therapy
Subjects:
Adipose-derived stem cells (ADSCs)
Hippo
TAZ
Osteogenesis
Bone regeneration
Online Access:http://link.springer.com/article/10.1186/s13287-018-0799-z

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http://link.springer.com/article/10.1186/s13287-018-0799-z

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