Seizure-like activity in hyaluronidase-treated dissociated hippocampal cultures

Seizure-like activity in hyaluronidase-treated dissociated hippocampal cultures

The extracellular matrix (ECM) plays an important role in use-dependent synaptic plasticity. Hyaluronic acid (HA) is the backbone of the neural ECM, which has been shown to modulate -amino-3-hydroxyl-5-methyl-4-isoxazolepropionate (AMPA) receptor mobility, paired-pulse depression, L-type voltage-de...

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Bibliographic Details
Main Authors: Maria eVedunova, Tatiana eSakharnova, Elena eMitroshina, Maya ePerminova, Yuri eZakharov, Alexey ePimashkin, Alexander eDityatev, Irina eMukhina
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Extracellular Matrix
Hyaluronic Acid
AMPA receptors
seizure
microelectrode array
Neuronal Network
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00149/full

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http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00149/full

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