Preparation of 2-heteroatom substituted 4-oxo-4-arylbutanoates via thio- and aza-Michael addition

Preparation of 2-heteroatom substituted 4-oxo-4-arylbutanoates via thio- and aza-Michael addition

Efficient regioselective conjugate additions of thiophenols and benzotriazole to 4-aryl-4-oxobut-2-enoates have been achieved under mild conditions. Thus a variety of 2-arylthio-4-oxo-4-arylbutanoates and 2- benzotriazolyl-4-oxo-4-arylbutanoates were conveniently synthesized in good to excellent...

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Bibliographic Details
Main Authors: Liu Huili, Lv Xin, Zhou Liejin, Yin Ruifeng, Wang Xiaoxia
Format: Article
Language:English
Published: Serbian Chemical Society 2012-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Michael addition
thiophenol
benzotriazole
4-aryl-4-oxobut-2-enoate
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391100202L.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391100202L.pdf

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