MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1

MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1

Abstract Background A high level of total cholesterol is associated with several lipid metabolism disorders, including atherosclerosis and cardiovascular diseases. ATP-binding cassette (ABC) transporter A1 (ABCA1) and miR-33-5p play crucial roles in atherosclerosis by controlling cholesterol efflux....

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Bibliographic Details
Main Authors: Qiong Xie, Jianqiang Peng, Ying Guo, Feng Li
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Cardiovascular Disorders
Subjects:
ox-LDL
Citrate synthase
ABCA1
miR-33-5p
Vascular endothelial cells
Online Access:https://doi.org/10.1186/s12872-021-02228-7

Internet

https://doi.org/10.1186/s12872-021-02228-7

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