ITAM signaling by Vav family Rho guanine nucleotide exchange factors regulates interstitial transit rates of neutrophils in vivo.

ITAM signaling by Vav family Rho guanine nucleotide exchange factors regulates interstitial transit rates of neutrophils in vivo.

In response to infection, neutrophils are quickly recruited from the blood into inflamed tissues. The interstitial migration of neutrophils is crucial for the efficient capture and control of rapidly proliferating microbes before microbial growth can overwhelm the host's defenses. However, the...

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Bibliographic Details
Main Authors: Daniel B Graham, Bernd H Zinselmeyer, Francesca Mascarenhas, Ryan Delgado, Mark J Miller, Wojciech Swat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2645696?pdf=render

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http://europepmc.org/articles/PMC2645696?pdf=render

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