Curcumin, but not Prima-1, decreased tumor cell proliferation in the syngeneic murine orthotopic bladder tumor model

Curcumin, but not Prima-1, decreased tumor cell proliferation in the syngeneic murine orthotopic bladder tumor model

OBJECTIVE: Cigarette smoking is the main risk factor for bladder cancer development. Among the mediators of this effect of smoking is nuclear factor-kappa B. Curcumin suppresses cellular transformation by downregulating the activity of nuclear factor-kappa B. Prima-1 is a compound that induces apopt...

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Bibliographic Details
Main Authors: Fábio T. Watanabe, Daher C. Chade, Sabrina T. Reis, Camila Piantino, Marcos Francisco Dall’ Oglio, Miguel Srougi, Katia R. M. Leite
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2011-01-01
Series:Clinics
Subjects:
Bladder cancer
Treatment
Curcumin
Prima-1
Apoptosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011001200019

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011001200019

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