Interleukin 1α Sustains the Expression of Inflammatory Factors in Human Pancreatic Cancer Microenvironment by Targeting Cancer-Associated Fibroblasts

Interleukin 1α Sustains the Expression of Inflammatory Factors in Human Pancreatic Cancer Microenvironment by Targeting Cancer-Associated Fibroblasts

The tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) is dynamic, with an extensive interaction between the stroma and tumor cells. The aim of this study was to delineate the cross talk between PDAC and cancer-associated fibroblasts (CAFs), with a focus on the mechanism creating the...

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Bibliographic Details
Main Authors: Vegard Tjomsland, Anna Spångeus, Johanna Välilä, Per Sandström, Kurt Borch, Henrik Druid, Sture Falkmer, Ursula Falkmer, Davorka Messmer, Marie Larsson
Format: Article
Language:English
Published: Elsevier 2011-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800011

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http://www.sciencedirect.com/science/article/pii/S1476558611800011

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