Modulation of 8-OH-DPAT-Induced Hypothermia by Imipramine in Rats

ABSTRACT: The effects of imipramine on 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), the 5-hydroxytryptamine (5-HT)1A-receptor full agonist, -induced hypothermia was examined in rats. Single administration of imipramine (30 mg/kg, i.p.) attenuated 8-OH-DPAT-induced hypothermia. This effect of...

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Bibliographic Details
Main Authors: Yoshihisa Kitamura, Hiroaki Araki, Kazuhiko Shibata, Yutaka Gomita, Yoshiro Yoshiro
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319325745