From Normal to Obesity and Back: The Associations between Mitochondrial DNA Copy Number, Gender, and Body Mass Index

From Normal to Obesity and Back: The Associations between Mitochondrial DNA Copy Number, Gender, and Body Mass Index

Mitochondrial DNA (mtDNA) encodes core subunits of oxidative phosphorylation complexes and, as a result of intricate regulatory crosstalk between nuclear and mitochondrial genomes, the total number of mtDNA copies fits the requirements of each cell type. Deviations from the physiological number of m...

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Bibliographic Details
Main Authors: Daria Skuratovskaia, Larisa Litvinova, Maria Vulf, Pavel Zatolokin, Konstantin Popadin, Ilia Mazunin
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
mtDNA copies
bariatric surgery
type 2 diabetes
obesity
ddPCR
Online Access:https://www.mdpi.com/2073-4409/8/5/430

Internet

https://www.mdpi.com/2073-4409/8/5/430

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