Cartilage constructs engineered from chondrocytes overexpressing IGF-I improve the repair of osteochondral defects in a rabbit model
Tissue engineering combined with gene therapy is a promising approach for promoting articular cartilage repair. Here, we tested the hypothesis that engineered cartilage with chondrocytes overexpressing a human insulin-like growth factor I (IGF-I) gene can enhance the repair of osteochondral defects,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AO Research Institute Davos
2013-04-01
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| Series: | European Cells & Materials |
| Subjects: | |
| Online Access: | http://www.ecmjournal.org/journal/papers/vol025/pdf/v025a17.pdf |