Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon

Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon

Chlamydia trachomatis (Ct) is the most common sexually transmitted bacterium with more than 131 million cases occurring annually worldwide. Ct infections are often asymptomatic, persisting for many years despite treatment. In vitro recovery from persistence occurs when indole is utilized by the orga...

Full description

Bibliographic Details
Main Authors: Naraporn Somboonna, Noa Ziklo, Thomas E. Ferrin, Jung Hyuk Suh, Deborah Dean
Format: Article
Language:English
Published: American Society for Microbiology 2019-07-01
Series:mBio
Subjects:
chlamydia trachomatis
indole
interferon gamma
sexually transmitted infections
trpa
tryptophan synthesis
Online Access:https://doi.org/10.1128/mBio.01464-19

Internet

https://doi.org/10.1128/mBio.01464-19

Similar Items