Icariin Augments Bone Formation and Reverses the Phenotypes of Osteoprotegerin-Deficient Mice through the Activation of Wnt/β-Catenin-BMP Signaling

Icariin has been mostly reported to enhance bone fracture healing and treat postmenopausal osteoporosis in ovariectomized animal model. As another novel animal model of osteoporosis, there is few publication about the effect of Icariin on osteoprotegerin-deficient mice. Therefore, the goal of this s...

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Bibliographic Details
Main Authors: Xiao-Feng Li, Hao Xu, Yong-Jian Zhao, De-Zhi Tang, Guo-Hua Xu, Jonathan Holz, Jing Wang, Shao-Dan Cheng, Qi Shi, Yong-Jun Wang
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/652317