Mask family proteins ANKHD1 and ANKRD17 regulate YAP nuclear import and stability

Mask family proteins ANKHD1 and ANKRD17 regulate YAP nuclear import and stability

Mask family proteins were discovered in Drosophila to promote the activity of the transcriptional coactivator Yorkie (Yki), the sole fly homolog of mammalian YAP (YAP1) and TAZ (WWTR1). The molecular function of Mask, or its mammalian homologs Mask1 (ANKHD1) and Mask2 (ANKRD17), remains unclear. Mas...

Full description

Bibliographic Details
Main Authors: Clara Sidor, Nerea Borreguero-Munoz, Georgina C Fletcher, Ahmed Elbediwy, Oriane Guillermin, Barry J Thompson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
YAP
hippo
signalling
Online Access:https://elifesciences.org/articles/48601

Internet

https://elifesciences.org/articles/48601

Similar Items