Rescuing loading induced bone formation at senescence.
The increasing incidence of osteoporosis worldwide requires anabolic treatments that are safe, effective, and, critically, inexpensive given the prevailing overburdened health care systems. While vigorous skeletal loading is anabolic and holds promise, deficits in mechanotransduction accrued with ag...
Main Authors: | Sundar Srinivasan, Brandon J Ausk, Jitendra Prasad, Dewayne Threet, Steven D Bain, Thomas S Richardson, Ted S Gross |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2936512?pdf=render |
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