Clinical trials of dual-target CAR T cells, donor-derived CAR T cells, and universal CAR T cells for acute lymphoid leukemia

Abstract The current treatment for pediatric acute lymphoblastic leukemia (ALL) is highly successful with high cure rate. However, the treatment of adult ALL remains a challenge, particularly for refractory and/or relapsed (R/R) ALL. The advent of new targeted agents, blinatumomab, inotuzumab ozogam...

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Bibliographic Details
Main Authors: Juanjuan Zhao, Yongping Song, Delong Liu
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Hematology & Oncology
Online Access:http://link.springer.com/article/10.1186/s13045-019-0705-x