The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer.

BACKGROUND: Otto Warburg observed that cancer cells are often characterized by intense glycolysis in the presence of oxygen and a concomitant decrease in mitochondrial respiration. Research has mainly focused on a possible connection between increased glycolysis and tumor development whereas decreas...

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Bibliographic Details
Main Authors: Christoph Ruckenstuhl, Sabrina Büttner, Didac Carmona-Gutierrez, Tobias Eisenberg, Guido Kroemer, Stephan J Sigrist, Kai-Uwe Fröhlich, Frank Madeo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2643009?pdf=render