Do the mutations of <it>C1GALT1C1 </it>gene play important roles in the genetic susceptibility to Chinese IgA nephropathy?
<p>Abstract</p> <p>Background</p> <p>The deficiency of <it>β</it>1,3 galactose in hinge region of IgA1 molecule played a pivotal role in pathogenesis of IgA nephropathy (IgAN). Cosmc, encoded by <it>C1GALT1C1 </it>gene, was indispensable to <i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-09-01
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| Series: | BMC Medical Genetics |
| Online Access: | http://www.biomedcentral.com/1471-2350/10/101 |