Lrg1 Regulates β (1,3)-Glucan Masking in Candida albicans through the Cek1 MAP Kinase Pathway

Lrg1 Regulates β (1,3)-Glucan Masking in Candida albicans through the Cek1 MAP Kinase Pathway

Candida albicans is an important source of systemic infections in humans. The ability to mask the immunogenic cell wall polymer β (1,3)-glucan from host immune surveillance contributes to fungal virulence. We previously reported that the hyperactivation of the Cek1 MAP kinase cascade promotes cell w...

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Bibliographic Details
Main Authors: Tian Chen, Andrew S. Wagner, Robert N. Tams, James E. Eyer, Sarah J. Kauffman, Eric R. Gann, Elias J. Fernandez, Todd B. Reynolds
Format: Article
Language:English
Published: American Society for Microbiology 2019-09-01
Series:mBio
Subjects:
gtpase
cdc42
rho1
ras1
rac1
mapk cascade
ste11
cek1
cell wall
β (1,3)-glucan
virulence
candida albicans
Online Access:https://doi.org/10.1128/mBio.01767-19

Internet

https://doi.org/10.1128/mBio.01767-19

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