Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial

Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial

Abstract Background The focus of this study is to identify particular microRNA (miRNA) signatures in exosomes derived from plasma of 435 human epidermal growth factor receptor 2 (HER2)-positive and triple-negative (TN) subtypes of breast cancer (BC). Methods First, miRNA expression profiles were det...

Full description

Bibliographic Details
Main Authors: Ines Stevic, Volkmar Müller, Karsten Weber, Peter A. Fasching, Thomas Karn, Frederic Marmé, Christian Schem, Elmar Stickeler, Carsten Denkert, Marion van Mackelenbergh, Christoph Salat, Andreas Schneeweiss, Klaus Pantel, Sibylle Loibl, Michael Untch, Heidi Schwarzenbach
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Medicine
Subjects:
MicroRNAs
Exosomes
Breast cancer
Triple negative
HER2-positive
Pathological complete response
Online Access:http://link.springer.com/article/10.1186/s12916-018-1163-y

Internet

http://link.springer.com/article/10.1186/s12916-018-1163-y

Similar Items