Crystal structure of the Sema-PSI extracellular domain of human RON receptor tyrosine kinase.

Human RON (Recepteur d'Origine Nantais) receptor tyrosine kinase is a cell surface receptor for Macrophage Stimulating Protein (MSP). RON mediates signal transduction pathways that regulate cell adhesion, invasion, motility and apoptosis processes. Elevated levels of RON and its alternatively s...

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Bibliographic Details
Main Authors: Kinlin L Chao, I-Wei Tsai, Chen Chen, Osnat Herzberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3405059?pdf=render