A New Long Noncoding RNA ALB Regulates Autophagy by Enhancing the Transformation of LC3BI to LC3BII during Human Lens Development

A New Long Noncoding RNA ALB Regulates Autophagy by Enhancing the Transformation of LC3BI to LC3BII during Human Lens Development

Autophagy is essential in lens organelle degradation. This study aimed to seek potential autophagy-associated long noncoding RNAs (lncRNAs) and their relative mechanisms in human lens development using the “fried egg” lentoid body (LB) generation system. The expression pattern of LC3B in differentia...

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Bibliographic Details
Main Authors: Qiuli Fu, Zhenwei Qin, Lifang Zhang, Danni Lyu, Qiaomei Tang, Houfa Yin, Zhijian Chen, Ke Yao
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
long noncoding RNA
lentoid bodies
induced pluripotent stem cells
lens
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117302615

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http://www.sciencedirect.com/science/article/pii/S2162253117302615

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