Classification of High-Grade Serous Ovarian Carcinoma by Epithelial-to-Mesenchymal Transition Signature and Homologous Recombination Repair Genes

Classification of High-Grade Serous Ovarian Carcinoma by Epithelial-to-Mesenchymal Transition Signature and Homologous Recombination Repair Genes

High-grade serous ovarian cancer (HGSOC) is one of the deadliest cancers that can occur in women. This study aimed to investigate the molecular characteristics of HGSOC through integrative analysis of multi-omics data. We used fresh-frozen, chemotherapy-naïve primary ovarian cancer tissues and match...

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Bibliographic Details
Main Authors: Min-Hwan Sohn, Se Ik Kim, Jong-Yeon Shin, Hee Seung Kim, Hyun Hoon Chung, Jae-Weon Kim, Maria Lee, Jeong-Sun Seo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Genes
Subjects:
ovarian cancer
high-grade serous carcinoma
gene signature
epithelial-to-mesenchymal transition
homologous recombination repair
Online Access:https://www.mdpi.com/2073-4425/12/7/1103

Internet

https://www.mdpi.com/2073-4425/12/7/1103

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